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“I went to Fyodor and said, ‘Hey, we’re getting all these great results in the clinic with CRISPR, but why hasn’t it scaled?” says Hu. Part of the reason is that most gene-editing companies are chasing the same few conditions, such as sickle-cell, where (as luck would have it) a single edit works for all […]
Jan 09, 2026Ravie LakshmananVirtualization / Vulnerability Chinese-speaking threat actors are suspected to have leveraged a compromised SonicWall VPN appliance as an initial access vector to deploy a VMware ESXi exploit that may have been developed as far back as February 2024. Cybersecurity firm Huntress, which observed the activity in December 2025 and stopped it before […]
The first thing you learn when you spend too long around Bitcoin is that everyone has a chart that “always works”, and everyone has a scar from the last time it didn’t. This week’s chart is making the rounds again, it’s the one that tracks Bitfinex margin longs, and it’s flashing a familiar change in […]
For most business leaders, the AI story began with a simple expectation: “I want to ask my company a question and get a correct answer in seconds.” Not a document.Not a dashboard.Not a spreadsheet. An answer. What followed instead was one of the biggest expectation gaps in modern enterprise technology. Phase One: The AI Dream […]
Macroscope helps you understand your code through AI-powered code review, automated PR descriptions, and real-time status reports Connect with Kayvon on Twitter and LinkedIn. This week’s shoutout goes to user Jesper Grann Laursen for winning a Populist badge on their answer to Exclude Table during pg_restore. TRANSCRIPT Ryan Donovan: Tired of database limitations and architectures […]
Fly’s new Sprites.dev addresses both developer sandboxes and API sandboxes at the same time 9th January 2026 New from Fly.io today: Sprites.dev. Here’s their blog post and YouTube demo. It’s an interesting new product that’s quite difficult to explain—Fly call it “Stateful sandbox environments with checkpoint & restore” but I see it as hitting two […]
Grok users aren’t just commanding the AI chatbot to “undress” pictures of women and girls into bikinis and transparent underwear. Among the vast and growing library of nonconsensual sexualized edits that Grok has generated on request over the past week, many perpetrators have asked xAI’s bot to put on or take off a hijab, a […]
Amazon could be taking another, even bigger swing at physical stores, this time with a Walmart-like supercenter. On Tuesday, the Orland Park Plan Commission in the Chicago suburb Orland Park, Illinois voted 6-1 to approve Amazon’s proposal to develop 35 acres of land for a 229,000-square foot retail center, as reported by The Information. The […]
CES 2026 is winding down in Las Vegas, as the consumer tech industry and everyone swarming around it begin their return flights home. Over the past few days, we saw a slew of announcements from mainstays like Nvidia, Sony, and AMD, along with smaller companies and startups vying for attention through the Unveiled event (CES’s showcase for new products) and across the show floor. As has […]
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